IDSA and SHEA have updated guidelines for 2017. Please see here for details.
Sometimes interpretation of Clostridium difficile testing can be confusing. See this page which helps interpret the test.
It will be located under “Infection Prevention” => Interpretation of Clostridium difficile testing.
Do probiotics prevent antibiotic associated diarrhea? A Welsh study published in The Lancet indicates that antibiotic-induced diarrhea is not prevented in the elderly by a daily dose of probiotics. Earlier research had shown potential, and prompted doctors to routinely prescribe antibiotics and probiotics together. The probiotic market had been estimated to reach $2.07 billion by 2015.
Approximately 10.8% of people in the probiotic group got antibiotic-associated diarrhea, compared to 10.4% of the control group. Researcher Stephen J. Allen concluded, “Our findings should discourage the use of microbial preparations for the prevention of AAD and C. difficile diarrhea.” He believes previous research showing promise was flawed because of microbial variation, small sample sizes, erroneous reporting, and poor trial designs.
- Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial; The Lancet, Early Online Publication, 8 August 2013 doi:10.1016/S0140-6736(13)61218-0
- Bloomberg News (8/7, Fourcade)
- MedPage Today (8/8)
This is the screen cast of a lecture titled “Outbreaks in extended care facilities (ECF)” given by Irfan Hafiz MD on April 19th 2013 at Centegra McHenry Hospital. It was co-sponsored by Centegra Health System and the McHenry County Dept. of Health.
Topics included in the lecture include:
- Identifying current and emerging infectious disease common to long term care facilities (LTCF).
- Describe preventive interventions for infectious disease in the context of LTCF.
- Describe the unique challenges facing LTCF in the context of infectious diseases.
For upcoming lectures please look at the calendar and filter by “Education Events”.
Recurrent refractory Clostridium difficile infection has been a cause of significant morbidity. There have been years of anecdotal case reports of successful fecal transplant. This study  published in the January 31st 2013 issue of New England Journal of Medicine describes resolution of symtoms in 13 of 16 patients treated with single duodenal infusion of feces.
Feces was collected on the day of infusion from prescreened volunteers, processed and administered within 6 hours of collection via nasoduodenal tube. The feces was diluted with 500 ml of sterile water, stirred, strained before administration.
All patients in the study first received oral vancomycin followed by bowel prep with 4 liters of macrogol solution on the last day of antibiotic treatment.
- Treatment of refractory/recurrent C. difficile-associated disease by donated stool transplanted via colonoscopy: a case series of 12 patients ↩
- Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients: methodology and results ↩
- Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection ↩
- Donor feces infusion for recurrent Clostridium difficile ↩