Limitation of certain anti-infectives to ID service

You may already be aware of the growing menace of global antimicrobial resistance. Among the measures to control the selection pressure it was felt that certain anti-infectives should be limited to the order of ID service.

Up until this time, only two anti-infectives had such limitation, polymyxin E (COLISTIN) and fidaxomicin (DIFICID).  Several other agents will now be part of the restricted list. As you can see from the limitation list below, a number of these anti-infectives are currently non-formulary and in general are not commonly used and should therefore be reserved for specific cases.

Ceftaroline TEFLARO NON   FORMULARY
Daptomycin CUBICIN NON   FORMULARY
Doripenem DORIBAX NON   FORMULARY
Fidaxomicin DIFICID NON   FORMULARY
Ganciclovir CYTOVENE NON   FORMULARY
Imipenem PRIMAXIN FORMULARY
Linezolid ZYVOX FORMULARY
Liposomal   Amphotericin AMBISOME FORMULARY
Polymyxin   E COLISTIN FORMULARY
Tigecycline TYGACIL NON   FORMULARY
Voriconazole VFEND FORMULARY

 

We feel that this is an important and appropriate step in maintaining the current level of antimicrobial resistance that we are presently seeing at Centegra Hospitals.  We are asking for your full support in this effort.  If you have a patient that requires one or more of the drugs listed above, an ID consult will now be required.

Thank you for time and cooperation in this very important matter.

From:
R. Damaraju, M.D. Co-Chair, Pharmacy & Therapeutics Committee
M. Hoffman, M.D. Co-Chair, Pharmacy & Therapeutics Committee