Surgical prophylaxis SCIP

Surgical procedure Approved antibiotics
Cardiac or Vascular Cefazolin, cefuroxime or vancomycin (see foot note) if allergy to beta lactam vancomycin or clindamycin
Hip or knee arthroplasty Cefazolin, cefuroxime or vancomycin (see foot note) if allergy to beta lactam vancomycin or clindamycin
Colon Cefotetan, Cefoxitin, Ampicillin/sulbactam OR [Cefazolin + Metronidazole], If β-lactam allergy: [Clindamycin + aminoglycoside], or [Clindamycin + Ciprofloxacin], or [Clindamycin + Aztreonam] or [Metronidazole with Gentamicin], or [Metronidazole + Ciprofloxacin]
Hysterectomy Cefotetan, Cefazolin, Cefoxitin, Cefuroxime or Ampicillin/sulbactam OR Clindamycin + ciprofloxacin OR Clindamycin + Aztreonam OR Metronidazole + Gentamicin OR Metronidazole + ciprofloxacin (CIPRO)

Notes

  • Vancomycin is acceptable with a physician/APN/PA/pharmacist documentation justification for its use (allergy to penicillin known MRSA, hospitalized >24 hrs; Cardiac valve surgery)
  • Levofloxacin 750mg may be substituted for Ciprofloxacin