Surgical prophylaxis SCIP

Surgical procedureApproved antibiotics
Cardiac or VascularCefazolin, cefuroxime or vancomycin (see foot note) if allergy to beta lactam vancomycin or clindamycin
Hip or knee arthroplastyCefazolin, cefuroxime or vancomycin (see foot note) if allergy to beta lactam vancomycin or clindamycin
ColonCefotetan, Cefoxitin, Ampicillin/sulbactam OR [Cefazolin + Metronidazole], If β-lactam allergy: [Clindamycin + aminoglycoside], or [Clindamycin + Ciprofloxacin], or [Clindamycin + Aztreonam] or [Metronidazole with Gentamicin], or [Metronidazole + Ciprofloxacin]
HysterectomyCefotetan, Cefazolin, Cefoxitin, Cefuroxime or Ampicillin/sulbactam OR Clindamycin + ciprofloxacin OR Clindamycin + Aztreonam OR Metronidazole + Gentamicin OR Metronidazole + ciprofloxacin (CIPRO)

Notes

  • Vancomycin is acceptable with a physician/APN/PA/pharmacist documentation justification for its use (allergy to penicillin known MRSA, hospitalized >24 hrs; Cardiac valve surgery)
  • Levofloxacin 750mg may be substituted for Ciprofloxacin